Health & Medicine

Ketamine: An old medication with newly discovered actions in pain and breathing regulation

Pain that lasts longer than the expected period of healing is tormenting a significant percentage of the population and is the leading cause of disability worldwide. Although medications are available to control it, its management often involves trial and error, especially in cases where specific nerve damage cannot be found. Professor Albert Dahan at the Leiden University Medical Center in […]

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Earth & Environment

Exiguobacterium degradation of polystyrene: Enlisting bacteria in the war against plastic

Polystyrene is a chemically stable recalcitrant plastic that pollutes many natural environments. Unfortunately, few mechanisms can break down this man-made polymer into its naturally occurring components. Research into the polystyrene-digesting capabilities of the bacteria genus Exiguobacterium sp RIT 594 by Dr André Hudson and his team at the Rochester Institute of Technology in New York, USA, has uncovered the specific […]

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Physical Sciences

FAME – the green revolution of conventional biodiesel

The global shift away from petrochemical production towards bio-based solutions has given a boost to conventional biodiesel producers. However, they’re facing a challenger ‘from the inside’ – renewable biodiesel. Undaunted, a team of chemists and engineers from Airable Research Lab in the USA, led by Dr Dylan Karis, has revealed that conventional biodiesel – or fatty acid methyl ester (FAME) […]

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Health & Medicine

Unlocking iodine’s true potential

Despite it being a cornerstone antibacterial application in hospitals, ‘iodine’ is often used with reservations about staining and toxicity. Such reservations have historical roots founded on unfortunate misconceptions that also mask the remarkable properties of an iodine solution’s active agent – molecular iodine. Dr Jack Kessler, Douglas C Spitz, and colleagues at I2Pure, USA, have demonstrated that molecular iodine is […]

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Health & Medicine

Should pre-anaesthesia consultations be done telephonically?

Anaesthesiologists play a crucial role in preparing a patient ahead of surgery, and not just physically. Pre-anaesthesia consultations are an opportunity to engage with patients, involve them in important choices, and consider these when making diagnostic, therapeutic, or palliative care decisions. Dr Sibylle Kietaibl at the Evangelical Hospital Vienna in Austria suggests such consultations should also consider patient preferences around […]

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Engineering & Technology

Digital twin for integration of design, manufacturing, and maintenance

Design, manufacturing, and maintenance of industrial equipment are usually managed separately, making them inefficient in terms of time and cost. Dr Ming-Liang Zhu, Dr Fu-Zhen Xuan and colleagues at East China University of Science & Technology develop the concept of digital twin technology to increase the efficiency of all phases that make up a product’s lifecycle. Their research offers a […]

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Biology

Microbiomes – the key to a healthier planet?

Microbiomes are communities of microorganisms living on or in animals, helping to keep them healthy. Changes in the composition of microbiomes could make wildlife more vulnerable to diseases which may be zoonotic – transmissible to humans – so monitoring them could help us to predict outbreaks of disease and protect global health. Dr Andrew Bartlow and colleagues at the Los […]

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Health & Medicine

Co-existence of hepatosteatosis and skeletal muscle fat infiltration

Accumulation of fat in the liver (hepatosteatosis) and muscle (myosteatosis) affects normal physiological functioning, leading to poorer health outcomes. But what is the concurrence of these two conditions in the general population, and are there common underlying mechanisms? Professor Julie Pasco and colleagues at Deakin University and Barwon Health in Australia investigate these metabolic alterations in a population-based study providing […]

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Thought Leaders

Healthier societies: Professor Kent Buse on tackling health and gender inequality

Professor Kent Buse, Co-founder and Co-director of Global Health 50/50, discusses the relationship between gender and health inequality. Alongside fellow Co-founder and Co-director, Professor Sarah Hawkes, Buse is leading the independent initiative to actively assess global health organisations on their gender equality credentials to stamp out discriminatory policies and practices. Buse is also the Director of the Global Healthier Societies […]

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Engineering & Technology

Trifluoromethylpyridine: Its chemistry and applications

Trifluoromethylpyridine (TFMP) and its intermediates are important ingredients for the development of agrochemical and pharmaceutical compounds. The presence of a fluorine atom and a carbon-containing pyridine are thought to bestow many of the distinctive physical–chemical properties observed with this class of compounds. Dr Masamitsu Tsukamoto and Mr Tadashi Nakamura, of Ishihara Sangyo Kaisha, Ltd, Japan, take a closer look at this […]

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