Articles
Cooling Cryosim drops for treatment of cough
A cough can significantly impact our quality of life, disrupting sleep and daily activities. Coughing is usually a symptom of benign viral infections – but sometimes a cough can linger long after the infection has cleared and persist for months. There is a need for new treatments to alleviate lingering coughs. Professor Edward T Wei at the University of California, […]
Dendrimers: Improving calibration standards for mass spectrometry
Soft-ionization mass spectrometry (MS) techniques for the analysis of peptides, proteins, and macromolecules are gaining popularity in the medical research community. Specifically, matrix-assisted laser-desorption/ionization (MALDI) and electrospray ionization (ESI) can identify high molecular weight compounds with accuracy and minimal fragmentation of the sample, but precise and regular calibration with standards of a known mass is needed. Professor Scott M Grayson […]
Unlocking the mechanism of action of arsenic trioxide in leukaemia
The blood cancer acute promyelocytic leukaemia (APL) has recently been transformed from a fatal condition to a curable one, thanks to the development of treatments including vitamin A1 and arsenic trioxide (ATO). Although very effective, the mechanism of action of ATO has remained unclear until now. Changing this is Professor Paul B Tchounwou and his team at Jackson State University, […]
Building a psychological toolbox: Actively using neuroplastic methods to develop lasting inner strengths
Social-emotional learning (SEL) makes use of the brain’s neuroplasticity to convert passing experiences into durable psychological resources embedded in altered neural structure or function. But most SEL is passive and inefficient, with limited gains for many people, in part due to the brain’s ingrained negativity bias. Dr Rick Hanson is a leading clinician in the field of emotional intelligence. He […]
Rethinking leadership in complex adaptive systems
Leadership is a cornerstone of business school syllabi, but it is usually focused on organisational leadership. But what about the leadership needed to deal with global issues that cross geographic, legislative, geopolitical, socio-economic, and structural boundaries, and demand the interplay between state, corporate and non-governmental actors? Professor Margaret F Sloan of James Madison University, in Virginia, US, considers such issues […]
Durability of wood – integration of experimental and numerical approach
If a building is to have a lifetime of fifty years or more, it is important to be able to predict how the construction materials will fare in that timespan. This is particularly challenging for natural materials like wood due to natural differences in the structure. Serena Gambarelli and Josipa Bošnjak at the University of Stuttgart, Germany, employ a hygro-mechanical […]
A new strategy for the treatment of chronic wounds
Wound healing is highly regulated, but oxidative stress (OS) can disturb this healing process in chronic wounds. To better understand the process of initiating chronicity, Dr Manuela Martins-Green and her colleagues at the University of California investigated the impact of increased OS levels on wound healing by stimulating chronic wound development in a diabetic mouse model. The team provides insight […]
A life in literature: An interview with Professor Nicholas Royle
Nicholas Royle is Professor of English at the University of Sussex and founding director of the Centre for Creative and Critical Thought. Since publishing his first work of criticism – Telepathy and Literature – in 1991, his creative output has been consistently varied and rewarding, blurring any firm conception of form or genre. Royle remains most widely known, perhaps, for […]
Cascading energy: Explaining fluctuations in the solar wind
Originating from the dynamic upper reaches of the Sun’s atmosphere, the influence of solar wind can be felt throughout the solar system. We sat down with Dr Charles Smith at the University of New Hampshire to discuss how the latest theories of fluid dynamics, combined with observations from spacecraft missions, can help us to understand turbulence in the interplanetary plasma. […]
Parachute science and Caribbean plastic pollution
Marine litter research in the Caribbean’s Small Island Developing States (SIDS) is imperative for protecting local communities and ecosystems from the effects of plastic pollution. Work to resolve the damage caused by marine debris, however, is being undermined by ‘parachute science’, where scientists from outside SIDS conduct research and leave without consulting or collaborating with local experts. Dr Aleke Stöfen-O’Brien […]