Uncovering critical cell death mechanisms for novel cardioprotective therapies

Mitochondria are required to produce the vast amount of energy that is required for the cell to beat.

Cell death is part of a natural process by which old cells are replaced by new, but it can also result from disease or injury. There are still many aspects of this process which are not fully understood. The laboratory of Dr Jason Karch, Baylor College of Medicine, aims to increase comprehension of the mechanisms behind cell death. If these […]

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Direct cardiac reprogramming to regenerate the heart

Direct cardiac reprogramming to regenerate the heart

Infarction causes the loss of a consequent number of cardiac muscle cells. Unable to self-regenerate, these cells are replaced by fibroblasts. This can lead to heart failure. Priyadharshni Muniyandi, doctoral researcher and Dr M. Sheikh Mohamed, Associate Professor at the Bio-Nano Electronics Research Centre, Toyo University, work on direct cardiac reprogramming. Their technique uses microRNA encapsulated in a non-viral nanocarrier: […]

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