Cell division Archives

Metabolic dysfunction: The liver and beyond

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Philipp Kaldis and colleagues have conducted extensive research to elucidate the mechanisms of liver diseases, focusing on metabolism and interorgan crosstalk.

The liver is the centre of our metabolism, with metabolic dysfunction playing a pivotal role in liver diseases and type 2 diabetes. Despite extensive study, the mechanisms underlying these pathologies remain largely unexplained. Professor Philipp Kaldis of Lund University, Sweden, has collaborated with fellow researchers to investigate the role of metabolites during metabolic dysfunction in these diseases. Motivated by the goal […]

The intricate world of the centrosome

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Dr Ryoko Kuriyama is a Professor at the University of Minnesota, Twin Cities. Alongside Dr Cody Fisher, she studies mammalian centrosomes, composite organelles responsible for the segregation of chromosomes during mammalian somatic cell division. Together, Kuriyama and Fisher, with the help of the United States National Science Foundation, investigate the detailed complexity of centrosome maturation, identifying the pericentriolar material protein […]

Shaping the harvest: What determines crop shape?

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There is a huge amount of diversity in the shape of different crops, be it a fruit such as tomato or a vegetable such as carrot. Ultimately, the appearance of a plant organ is determined by different cellular control mechanisms. However, it is not known whether these mechanisms are similar across various species in the Plant Kingdom. Dr Esther van […]

Unravelling the secrets of the cell with suspended microchannel resonators

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Researchers can learn much about the properties of many materials simply by weighing them. In cell biology, repeatedly measuring the mass of a cell reveals how fast the cell grows. However, this is very challenging: the mass of a single-cell is extremely difficult to measure with enough accuracy and without perturbing the cell. The laboratory of Dr Scott Manalis at […]

A hitherto unseen matrix involved in cell division is revealed

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Cell division has been fascinating researchers for decades. This process could not occur without the spindle to organise the chromosomes neatly in two sets, one for each daughter cell. It’s commonly accepted that the spindle is formed by a series of filaments that puts chromosomes into place, but there may be more to it than that. This is certainly the […]