collagen Archives

The BEST lines for skin surgery: A new paradigm

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To minimise scarring, skin surgeons are guided by Langer lines and wrinkle lines, first identified over a century ago. Although based on limited data from cadavers, these historical studies have steered skin surgery for both incisions and excisions until recently. In a groundbreaking, first-of-its-kind study, Dr Sharad Paul at the Auckland University of Technology in New Zealand uses real-time skin […]

The role of water dynamics in age-related bone weakening

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Dr Valerie Welborn uses the density functional theory to understand how water molecules interact and bind to bone, and how the physiological environment may have an effect

The interaction of water with biological tissues plays crucial roles in maintaining cells and keeping complex organisms alive and healthy. Dysfunctions in biological processes involving water can lead to pathologies or death. For instance, age-related dehydration in bones leads to bone weakening with more frequent fractures, although the origin of this process is still poorly understood. Using powerful computational techniques, […]

Cell culture protocols for growing human keratinocytes in the laboratory

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Dr Hitomi Fujisaki studies human epidermal keratinocytes (skin cells).

Dr Hitomi Fujisaki, Senior Research Scientist at Nippi Research Institute of Biomatrix in Japan, studies human epidermal keratinocytes (skin cells) and cancer cells using two- and three-dimensional type I collagen substrates. Through her research, she aims to understand more about the ways in which these cells interact with the substrate that they are grown on, and how this relationship can […]