Is the magic in the muscle? Targeting skeletal muscle to improve cardiometabolic function in ageing

The Butcher Lab investigates the interplay of muscle mass and skeletal muscle on cardiovascular disease, obesity and ageing.

Dr Joshua T Butcher and his team from the Oklahoma State University College of Veterinary Medicine, USA, investigate the similarities between the co-morbidities associated with obesity and ageing, and specifically how skeletal muscle mass and function can be used to uncouple diseases from accompanying pathology. While we all know that exercise is beneficial for weight loss, an important underlying benefit […]

Read More… from Is the magic in the muscle? Targeting skeletal muscle to improve cardiometabolic function in ageing

Uncovering critical cell death mechanisms for novel cardioprotective therapies

Mitochondria are required to produce the vast amount of energy that is required for the cell to beat.

Cell death is part of a natural process by which old cells are replaced by new, but it can also result from disease or injury. There are still many aspects of this process which are not fully understood. The laboratory of Dr Jason Karch, Baylor College of Medicine, aims to increase comprehension of the mechanisms behind cell death. If these […]

Read More… from Uncovering critical cell death mechanisms for novel cardioprotective therapies