immunity Archives

Malaria modelling: An optimal control problem

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Professor Wandi Ding uses mathematical modelling to allow for control variables when modelling complex biological systems; in this case determining the best way to control wild mosquito populations through the release of sterile insects to reduce the impact of malaria

Malaria, a life-threatening mosquito-borne disease, is a leading cause of death and infection in many developing countries. Using mathematical modelling, Professor Wandi Ding, Middle Tennessee State University, USA, and her colleagues investigate optimal control of malaria, using both the sterile insect technique and insecticide-treated nets. Their simulations show that a combination of both strategies results in a more rapid elimination […]

Lateral flow test detects SARS-CoV-2 neutralising antibodies

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Novodiax Inc., under the guidance of Dr Jianfu Wang, has produced a novel lateral flow device called CoNAb. The device detects neutralising antibodies (NAbs) against SARS-CoV-2 (the virus responsible for COVID-19). Measuring NAbs is important to help us determine whether vaccination programmes are effective by measuring the level of immunity of vaccine recipients. They are also a vital tool for […]

Viral encephalitis and virus-mediated memory disorders

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Prof Klein researches viral infections that target neurons.

Viral encephalitis is a debilitating consequence of viral infections: invasion of the brain by viruses causes an inflammation that, even months or years after recovery from the viral infection, can impair cognitive functions such as learning and memory. Prof Robyn S. Klein from Washington University School of Medicine has developed novel animal models and approaches to study virus-mediated memory disorders, […]

Human Leukocyte Antigens: The missing link in Alzheimer’s disease etiology

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Viral infections such as the herpes virus have been implicated in Alzheimer’s disease risk.

Alzheimer’s disease is a huge socioeconomic burden in developed countries. Recently, viral infections such as the herpes virus have been implicated in Alzheimer’s disease risk. However, it is unclear what the link between the two is. Professor Lisa M. James of the University of Minnesota, in collaboration with Dr Apostolos Georgopoulos and Dr Spyros Charonis, has utilised computational biology to […]

The biology of ageing

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Biology of ageing Dr Nan-ping Weng Research Outreach

What causes ageing? Is it inevitable? Could it be slowed or even reversed? Humans have wanted to know the answer to these questions ever since we became aware of our own mortality. Despite the tremendous advances that have been made in our scientific understanding over the past century, ageing remains one of the greatest mysteries in biological science. But scientists, […]