How ubiquitin determines the fate of our proteins

How ubiquitin determines the fate of our proteins

Regulation of the multitude of protein-protein interactions that take place in the cell is essential. HECT E3 ubiquitin ligases play an important role in regulating protein functions and maintaining cellular health. However, many questions about their biological functions remain unanswered. Working at the interface of biochemistry and biophysics, Dr Donald Spratt from Clark University in Massachusetts, uses NMR spectroscopy to […]

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