lipids Archives

Chemical synthesis to tackle tuberculosis

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Dr Jeffrey Buter has been researching the chemical biology of the parasite that causes TB to understand how the particular cell wall of Mtb enables it to avoid the immune response of the host

Tuberculosis (TB) – the world’s most deadly bacterial infectious disease – kills around 1.5 million people every year, and its treatment remains challenging. Dr Jeffrey Buter at the University of Groningen, the Netherlands, has been researching the chemical biology of Mycobacterium tuberculosis (Mtb), the parasite that causes TB. Buter believes that understanding the structure–activity relationship of the components, in particular […]

Optimal lipid metabolism with disease-preventing functional foods

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Professor Harjinder Singh and Dr Alexander Acevedo-Fani research lipid digestion and the possibility of altering emulsion interactions

Dietary lipids (fats) from plant and animal sources are important components of the human diet as they provide essential nutrients for growth and development. However, overconsumption of lipid-rich foods can lead to hyperlipidaemia – a key risk factor for metabolic diseases, such as cardiovascular diseases and diabetes. Modulating lipid digestion and absorption through the design of food structures, matrices and […]

Myocardial lipid metabolism: Targeting CD36 to treat cardiac disease

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Jan Glatz researches a transmembrane protein, CD36, which regulates cellular lipid metabolism and can lead to treatments to improve healthy heart contraction and treat cardiac disease.

Jan Glatz, Emeritus Professor of Cardiac Metabolism at Maastricht University, conducts research into the transmembrane protein CD36, which regulates cellular lipid metabolism. CD36 facilitates the uptake of long-chain fatty acids in cardiac muscles while the recycling of CD36 between endosomes and the sarcolemma regulates this uptake. Heart diseases are commonly associated with changes in the uptake and use of its […]

Common beans: A sustainable and inexpensive super food to fight against CVD

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Legumes, such as common beans, are well known for their health benefits, including their ability to lower blood cholesterol and lipid levels. However, prior to consumption, beans need to be cooked or processed. These techniques often cause changes in the bean matrix, which can potentially influence their positive physiological effects. Dr Cristina Fernández-Fraguas, Assistant Professor at Virginia Polytechnic Institute and […]