Maryland Archives

Synthesising circular RNA is as easy as PIE

Written by

Dr Jason Rausch has developed a new protocol for synthesising large, complex, artificial circRNA which enhances the research in this field, as these have significant functionality and can also be genetic biomarkers for certain diseases

Naturally occurring circular loops of RNA, circRNAs, are the result of rare but significant backsplicing events. They are found throughout the eukaryotic domain and have been associated with pathological states such as tumour growth and suppression. Existing molecular techniques have taught us a great deal about circRNAs, but they are often difficult to implement and limited in scope. Dr Jason […]

Maryland Stem Cell Research Fund: Cutting-edge regenerative medicine

Written by

The Maryland Stem Cell Research Fund (MCSRF) is devoted to developing and supporting innovative research into all aspects of stem-cell-based technologies. Through its diverse program structure, the MSCRF is intimately involved in every stage of the stem cell journey – from pre-clinical lab discovery to clinical patient trials. Importantly, it remains forward thinking, ensuring the next generation of researchers have […]

Controlled cortical impact: The animal model that may change brain injury

Written by

Traumatic brain injury (TBI) is one of the leading causes of disability and death around the world. To compound this problem, many patients go on to develop anxiety and with little known about the pathophysiology behind this complication, long-lasting and effective treatments are lacking. Using an animal model known as the controlled cortical impact (CCI) model, Dr Ann Marini and […]