Tag: Parkinson’s
When the body turns against itself: Amyloid-based diseases
Often, the body is its own worst enemy. Diseases such as cancer are caused by faults in the natural replication processes of our own cells. It is thought that both Parkinson’s and Alzheimer’s disease may be caused by amyloids – aggregates of our own proteins that can disrupt nerve signalling and other functions. Dr H. Robert Guy of Amyloid Research […]
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Regulators of protein degradation as potential treatments for neurodegenerative disease
Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, are characterised by the accumulation of misfolded and damaged protein aggregates. Normally, proteins that are damaged or malfunctioning are destroyed by the ubiquitin proteasome system (UPS). However, the UPS itself is impaired in several instances of neurodegenerative diseases. Dr David Smith and his team at the School of Medicine, University of West […]