Proteomics reveals new possibilities in the fight against infection

Proteomics reveals new possibilities in the fight against infection

The work of Dr Jennifer Geddes-McAlister at the University of Guelph investigates the interactions between hosts and pathogens to uncover new treatment options to combat infections. Her lab uses a range of techniques centered around proteomics, the study of proteins, to progress knowledge of fungal and bacterial infections in humans and agricultural crops. The results of this research can be […]

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Systems biology and metabolic networks predict heterosis

Identifying plant traits in the lab.

Heterosis or hybrid vigour is the improved function of a desirable quality in hybrid offspring. Predicting heterosis would mean that plant and animal breeding need not depend on time-consuming and costly field tests of numerous combinations. Dominique de Vienne, Professor at the University Paris-Saclay, France, uses metabolic networks and systems biology to study heterosis. Modelling metabolic systems has relied on […]

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Open-source bioinformatic solutions for ‘Big Data’ analysis

In this research article: Drs Griffin and Jagtap’s research focuses on the Galaxy-P project – developing, testing, optimising and applying multi-omics software tools to a variety of biological questions, including cancer and big data research.

Drs Tim Griffin and Pratik Jagtap along with the Galaxy-P team from the University of Minnesota are working to develop workflows on an open source platform for the analysis of multi-omic data. They are currently focusing on using a Galaxy-based framework to investigate the integration of genomic datasets with mass spectrometry-based ‘omics’ data. But in the long term, they aim […]

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