Health & Medicine
Bidirectional relationship between chronic pain and insomnia
Dr Aubrey Husak, internal medicine resident at the Ohio State University, and Dr Matthew Bair, Core Investigator at VA HSR&D Center for Health Information and Communication and Associate Professor at Indiana University School of Medicine, carried out a review on the bidirectional relationship between chronic pain and insomnia. They found common comorbidities, including depression, anxiety, suicidal ideation, and catastrophising. Patients […]
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The trials and tribulations in the drug discovery cycle: A particular case for Alzheimer’s disease
As people live longer lives, the spectre of Alzheimer’s disease will only grow. Scientists now know that the amyloid beta (Aβ) peptides are important for treating Alzheimer’s, particularly Aβ42 which aggregates into the amyloid plaques that trigger the disease. Researchers have been looking to target γ-secretase – the enzyme that creates pathogenic Aβ42 affecting the relative abundance of short Aβ […]
A paradigm shift for fluid management in surgery
Advances in modern surgery have been dependent upon advances in anaesthetic management. However, anaesthesia can have detrimental effects, as it is usually associated with reduced blood pressure, cardiac output and oxygen delivery. To counteract these changes, large quantities of intravenous fluids have been administered both during and often for many hours post-surgery. This was in an attempt to maintain blood […]
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COVID-19 and its variants:
How N95 (hi-fi) masks can protect us
One of the defining issues of the COVID-19 pandemic and efforts to prevent its spread is inter-household transmission. Among the many policies and guidelines implemented, masks have been one of the most important and are now required wearing in the public spaces of many countries. But what if the masks we currently wear aren’t good enough? Researcher Devabhaktuni Srikrishna models […]
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How N95 (hi-fi) masks can protect us
Photobiomodulation therapy and its effects on muscle damage recovery
Dr Jamie Ghigiarelli from Hofstra University investigated the effects of whole-body photobiomodulation (red light) therapy (PBMT) administered before and after high-intensity training on 12 male participants. There lacks evidence on the effects of PBMT on larger muscle groups, as handheld devices to treat localised muscle tissues is the conventional method of instrumentation. This study showed no statistical significance but notably […]
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Management of weight gain in tube-fed children with neurodisabilities
Due to reduced levels of physical activity in children with cerebral palsy or other neurodisabilities, there is a risk of tube-fed individuals becoming overweight or obese if their feed contains an excess of calories. Nestlé Health Science provide a nutritionally complete, lower energy formula, Peptamen® Junior 0.6, that can be used to overcome this problem. Peptamen® Junior 0.6 is a […]
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The CEASE approach: A framework to tackle COVID-19 and other microbial threats
While the COVID-19 virus continues to spread in many countries worldwide, some researchers are investigating the implications of regularly using antimicrobial products and antibiotics, which could contribute to a concerning phenomenon known as antimicrobial resistance (AMR). Dr Teddie Rahube at Botswana International University of Science and Technology has recently developed CEASE, an approach that addresses some of the challenges associated […]
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The Benefits of Exercise on the Mind
Exercise has long been advocated as a way to enhance physical health, but it has also been shown to have several benefits on the mind. More recently, research has focused on how exercise can improve cognitive function. Over the past three decades, Drs Phillip D. Tomporowski and Caterina Pesce from the University of Georgia and the University of Rome, respectively, […]
Tracking how SARS-CoV-2 mutates around the world during COVID-19 pandemic
The COVID-19 pandemic is an ongoing global health crisis caused by the SARS-CoV-2 strain of coronavirus. The SARS-CoV-2 virus mutates as it spreads, and monitoring these mutations and their distribution could provide information relevant for the treatment and control of the disease. Santiago Justo Arévalo (Ricardo Palma University, Peru) and his colleagues have analysed the progress of several mutations across […]
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Probing Cancer: Immunotherapy and Molecular Imaging
The Singapore-based Cancer ImmunoTherapy Imaging (CITI) programme is a Singapore-wide collaborative research group, comprising 12 research institutes. CITI’s efforts are focused on the discovery and application of peptide-based imaging probes, which target immunotherapy treatment response biomarkers. Dr Edward G Robins, Head of Radiochemistry at the Singapore Bioimaging Consortium and Deputy Director of the NUS Clinical Imaging Research Centre, alongside his […]
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