Angiogenesis Archives

A new strategy for the treatment of chronic wounds

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A number of people are working in what looks to be a scientific laboratory. Everyone is wearing white coats, and one woman is leaning against a countertop. Dr Manuela Martins-Green investigates the impact of increased OS levels on wound healing by stimulating chronic wound development in a diabetic mouse model.

Wound healing is highly regulated, but oxidative stress (OS) can disturb this healing process in chronic wounds. To better understand the process of initiating chronicity, Dr Manuela Martins-Green and her colleagues at the University of California investigated the impact of increased OS levels on wound healing by stimulating chronic wound development in a diabetic mouse model. The team provides insight […]

AMP-activated kinase as a therapeutic target in prostate cancer

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Prostate cancer is one of the leading causes of mortality among men worldwide.

Pharmacological treatment of prostate cancer has advanced significantly in recent years. However, while the newest therapies are initially effective in reducing tumour size, most patients eventually develop drug resistance and the recurrence of malignant spread. Professor Inés Díaz-Laviada and her team at the Alcala University in Madrid, Spain, have demonstrated that long-term treatments may induce the transformation of cancer cells […]

RNA sequencing reveals secrets of skin aging

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As we age, so does our skin. One of the factors that affects how quickly skin appears to age is exposure to UV light. Dr Jeong-Sun Seo of Seoul National University Bundang Hospital, Republic of Korea, is investigating how UV light affects skin aging at the genetic level. Using RNA sequencing data, Dr Seo and his team demonstrate that some […]