Tag: Microbiome
Nivolumab against lung cancer: How is the gut–lung axis involved?
The study of the gut microbiome, which is the total of all the microbes living in the intestines, has been shown to not only play an important role in the health of the bowel itself, but also in the health of distant organs such as the lungs. Lung cancer is one of the diseases that is often difficult to treat […]
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Controlling Salmonella in the poultry gut: Diversity is key
When microorganisms that interact in a specific environment suppress the growth of pathogens, researchers call this ‘pathogen exclusion’. Salmonella is found in poultry intestines and can harm both the birds and humans. To control Salmonella growth, a balance between microorganisms that colonise the poultry gut is necessary. This involves complex interactions between microbes that we don’t yet fully understand. Dr Margie […]
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A new strategy for the treatment of chronic wounds
Wound healing is highly regulated, but oxidative stress (OS) can disturb this healing process in chronic wounds. To better understand the process of initiating chronicity, Dr Manuela Martins-Green and her colleagues at the University of California investigated the impact of increased OS levels on wound healing by stimulating chronic wound development in a diabetic mouse model. The team provides insight […]
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Impact of dietary protein on cat health and wellbeing
Compared to dogs, cats require higher levels of protein in their diet to remain healthy. Based on current recommendations, commercially available cat food contains between 28% and 55% protein for cats of different ages and health conditions. Dietary protein levels are thought to influence disease susceptibility by affecting gut microbial communities. Dr Dayakar Badri and Dr Matt Jackson of Hill’s […]
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The role of gut microflora in mucosal immunity
The microbiome is of recent interest in mucosal immunity. Dr Gary Huffnagle and colleagues at the University of Michigan have identified a variety of intestinal microflora members which can metabolically communicate with host cells and regulate mucosal immunity. Accumulating evidence suggests that various metabolites produced by hosts and microbiome members and their crosstalk are more important than previously thought. Understanding […]
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Scalp microbiome gets to the root of dandruff
Dandruff is an extremely common cosmetic condition, but one that remains often difficult to treat. Research scientists Sally Grimshaw, Elaine Xu and Dr Barry Murphy, of Unilever R&D, have carried out a detailed genetic investigation of the scalp microbiome: the community of bacteria, fungi and other microorganisms that live on the scalp skin. Their findings suggest that both bacteria and […]
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When grow healthy rhymes with grow happy
Happiness is acknowledged as a new goal of global policies. Parents play an important role in a child’s happiness, but what skills are needed to build a happy childhood and a solid foundation for happiness in later life? A complex approach, integrating parenting, social relationships, play, nutrition, physical activity and sleep is required. And ultimately, a happy child has more […]
Integrating molecular epidemiology and microbiome science
How cancer patients respond to therapy
Understanding the variation in responses to cancer therapeutics would create better treatment for many patients and provide an important basis for further research into new or personalised treatments. It is understood there is a connection between patient response to treatment and their microbiome. However, there is currently a lack of consensus on the microbial signatures present in responsive versus unresponsive […]