oxidation Archives

How oxidative stress contributes to neurodegenerative diseases

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Hyslop and Chaney use biochemical and computer molecular modelling to probe interaction between H2O2 and GAPDH to identify new molecular targets for treating neurodegeneration and neurodegenerative diseases.

The human brain relies on a constant energy supply that when compromised, neurodegenerative disease ensues, initially disrupting nerve cell communication followed by nerve cell death. Paul Hyslop and Michael Chaney investigate fundamental mechanisms driving neurodegenerative disease, to identify therapeutic interventions. They focus on how an enzyme integral to energy supply to nerve cells, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) – is inhibited and […]

Cut of the crop: High-yields of non-browning eggplant via genome editing

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Ongoing research at the Khalifa Center for Genetic Engineering and Biotechnology, UAE investigates high-yielding yet non-browning eggplants using genetic modification.

Eggplant is cultivated globally – but its production is fraught with issues affecting the crop’s overall yield and post-harvest properties. The fruit can be less appealing when damaged or cut due to the enzymatic browning of tissues. Cultivating high-yielding yet non-browning eggplants is an area of ongoing research at the Khalifa Center for Genetic Engineering and Biotechnology, UAE. The researchers […]

Triharmony/Trilemma of Carbon Assets in tropical peatland

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The water status of tropical peatlands regulates carbon emissions. From this, Osaki and colleagues are developing the Water–Carbon Interaction Model from which they estimate carbon flux related to human activity and climate change.

Tropical peatlands provide globally important reservoirs of water and carbon, and the cycles of these two elements are intricately connected. At Hokkaido University, Sumitomo Forestry Co, Ltd, Japan, and BRIN, Indonesia, scientists have developed a model for mapping carbon emissions from tropical peatlands. Their integrated monitoring, reporting, and verifying (iMRV) system measures dynamic changes in water and carbon cycles, biomass […]