All’s swell: Greener replacements for hazardous solvents in peptide synthesis

Greener replacements for hazardous solvents

There is growing awareness of the impact that solvents have on pollution, energy usage, contributions to air quality, and climate change. Consequently, sustainable solvents are a topic of growing interest, both within the research community and the chemical industry. A research team at Ipsen, Dublin, are forging the way ahead in the development of new, greener ways of manufacturing. Notably, […]

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Controlling aggregation in monoclonal antibody therapeutics

Monoclonal antibodies (mAbs) have become the most important form of protein therapeutic and represent five of the top ten selling drugs by revenue worldwide. mAbs bind monospecifically to certain cells or proteins. The objective is that this treatment will stimulate the patient’s immune system to attack those cells. Despite the many advantages of antibodies as therapeutics, their development is complicated […]

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Amino acids bombarded with ionising radiation – what breaks first?

Radiation can cause abnormal cellular behaviour.

Ionising radiation, including high-energy electrons, is usually something best avoided. However, nuclear accidents and even medical tools mean that human tissue is occasionally exposed to it. After the ‘Atomic Age’ of the mid-1900s, understanding the effect of radiation on the human body has been recognised as of paramount importance. Dr Jelena Tamuliene’s most recent research at Vilnius University is into […]

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