What can peptide-coated nanoparticles tell us about the causes of dementia?

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Kazushige Yokoyama, Professor of Chemistry at the State University of New York Geneseo College, investigates how peptides interact. Along with Akane Ichiki, an undergraduate student at the institution, his team have been investigating the peptides involved in fibrillogenesis, the process which occurs in the brain to form aggregates responsible for some of the symptoms involved in neurodegenerative diseases like Alzheimer’s […]

Unravelling the properties of membrane proteins

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30 years ago Matthias Wilm laid the scientific foundation for a methodology which today facilitates the synthesis and self-assembly of lipid membranes with proteins, granting insight into a complexity that has evolved over a million years of membrane protein evolution. From a biomedical to an environmental context, the use of molecular beams promises radical changes to how scientists solve problems […]

Extending the half‑life of therapeutic peptides

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This article is about Dr Alhamadsheh’s research which combines synthetic organic chemistry with biochemistry and molecular biology to study protein-protein interactions.

Dr Mamoun Alhamadsheh is Associate Professor at the University of the Pacific, Thomas J. Long School of Pharmacy and Health Sciences, California. He heads a multi-disciplinary team working in the field of protein-protein interactions. Their research is focused on the development of new treatments for diseases caused by protein aggregation, including Alzheimer’s disease and transthyretin amyloidosis. Their current work in […]