NMR2: A highly accurate approach to protein-ligand binding

A novel method to determine accurately and efficiently the structure of the receptor binding sites in protein-ligand complexes promises to revolutionize drug discovery. Dr Julien Orts and his collaborators at the Swiss Federal Institute of Technology are developing a powerful and general technique, based on liquid nuclear magnetic resonance (NMR), to shed light on the details of how proteins interact […]

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Extending the half‑life of therapeutic peptides

This article is about Dr Alhamadsheh’s research which combines synthetic organic chemistry with biochemistry and molecular biology to study protein-protein interactions.

Dr Mamoun Alhamadsheh is Associate Professor at the University of the Pacific, Thomas J. Long School of Pharmacy and Health Sciences, California. He heads a multi-disciplinary team working in the field of protein-protein interactions. Their research is focused on the development of new treatments for diseases caused by protein aggregation, including Alzheimer’s disease and transthyretin amyloidosis. Their current work in […]

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