programmed cell death Archives

One cell’s death is a microbe’s DINNR: How intestinal bacteria use our dying cells as fuel

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Dr CJ Anderson and Professor Kodi Ravichandran research the relationship between programmed cell death and bacterial infections in the intestinal tract, with an aim to understand the potential impact that this could have on chemotherapy patients

Until now, a great deal has remained unknown about the relationship between programmed cell death and bacterial infections. However, recent work by Dr CJ Anderson and Professor Kodi Ravichandran from VIB-UGent, Belgium, has shed new light on this topic and introduced a new layer to the complex host–pathogen interaction. The team has shown that dying mammalian cells produce and shed […]

Deeper insights into cell death and survival

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The intricate balance between cell death and survival is essential for normal development and for preventing diseases such as cancer and autoimmunity. Ronald Jemmerson at the University of Minnesota contributed to the seminal discovery that cytochrome c (Cyt c) plays a key role in the onset of apoptosis (programmed cell death). His laboratory also established that leucine-rich alpha-2-glycoprotein-1 (LRG1) binds […]

Reprogramming the immune system for personalised immunotherapy against cancer

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For decades, researchers have strived to understand how the immune system recognises and fights cancer, ultimately aiming to exploit and augment these processes to create more effective cancer therapies. Dr Richard Koya, Associate Professor of Oncology, Associate Director of the Center for Immunotherapy, and Director of the Vector Development & Production Facility at Roswell Park Cancer Institute is a prominent […]