oncology Archives

Brain Awareness Week 2022

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March 14 marks the start of Brain Awareness Week! Spearheaded by the Dana Foundation, the importance of brain research is catapulted onto the global platform between 14th–20th March 2022 – and cerebral successes in the field are celebrated. Research into the brain is vital for saving lives, increasing quality of life and explaining how ‘the little grey cells’ control our […]

World Cancer Day 2022: Innovations in cancer research

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Despite cancer being a leading cause of death worldwide, detecting cancers early enough to treat them remains a significant challenge. World Cancer Day, held annually on February 4, presents an opportunity to celebrate the advances that have been made, and to reflect on the work still to be done. This blog post brings together five Research Outreach articles that outline […]

Gender equality in oncology: The importance of representation

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Progress in gender equality in oncology is the key to innovation and leads to the best possible patient outcomes.

The field of oncology has a gender imbalance, with women only occupying a small number of leadership positions. So how can we improve gender equality in oncology? Dr Pilar Garrido, Dr Anna Sophie Berghoff, Dr Cristiana Sessa and colleagues, from the European Society for Medical Oncology (ESMO)’s Women for Oncology (W4O) Committee, are monitoring the representation of female oncologists. Through […]

A new weapon to boost cancer immunotherapy

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The 4SC team monitors the expression of relevant genes in the tumours of patients before and after administration of domatinostat.

In recent years, immunooncology has paved new avenues for effective treatment across cancer types. In addition to cytotoxic chemotherapy, we can now harness the power of the human immune response against malignant cells. However, immunotherapy is not perfect, and as always, cancer has mechanisms to evade these attacks. Dr Svetlana Hamm, Head of Research and Translational Medicine at 4SC in […]

The adaptive cancer cell: How metastases evolve to resist treatment

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PACCs make up a rare but stable population in standard cell culture.

Species adapt to survive in a changing environment through the process of evolution. Evolutionary processes can also take place at the cellular level. Dr Sarah Amend of Johns Hopkins University, Baltimore, USA, is investigating poly-aneuploid cancer cells (PACCs). These large, DNA-laden cells, which are more common in metastatic cancer, develop evolvability: the capacity to evolve. Dr Amend believes that targeting […]

Innovation in oncology drug development: A focus on patient benefits

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Innovation in oncology drug development is driving more efficient and effective development of new cancer treatments. This innovation is providing cancer patients unprecedented access to new therapies. Dr Brian Huber, Vice President of Therapeutic Areas, Drug Development and Consulting at ICON and Matthew Huber, a scientist in the emerging biotechnology sector focused on developing innovative oncology medicines, have conducted a […]

Reprogramming the immune system for personalised immunotherapy against cancer

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For decades, researchers have strived to understand how the immune system recognises and fights cancer, ultimately aiming to exploit and augment these processes to create more effective cancer therapies. Dr Richard Koya, Associate Professor of Oncology, Associate Director of the Center for Immunotherapy, and Director of the Vector Development & Production Facility at Roswell Park Cancer Institute is a prominent […]