Improved formulations of nicotinamide riboside: A promising treatment for age-related disorders

an array of samples of nicotinamide riboside

Nicotinamide adenine dinucleotide (NAD+) is a co-enzyme involved in fundamental metabolic roles. Its levels decrease with aging, causing the development of age-related pathologies. NAD+ levels can be replenished by the intake of nicotinamide riboside (NR), a vitamin B3 analogue, which is naturally converted to NAD+. Regular use of NR supplementation is associated with improved outcomes in several cardiovascular, neurodegenerative, and […]

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Mutant protein in Siamese cats may be involved in neurodegenerative disorders

Dr Niesman studies mutant tyrosinase in feline brain cells.

Siamese cats and humans share the same pathology when it comes to neurodegenerative disorders, such as Alzheimer’s disease. Dr Ingrid Niesman, based at San Diego State University, USA, believes it’s all down to a mutation in a protein called tyrosinase. The researcher wants to understand the impact of this malfunctioning protein, as well as use these cats as a basis […]

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