Health & Medicine

Developing a novel inhaled therapeutic for the treatment of bronchiolitis obliterans syndrome

Breath Therapeutics – a Zambon Group Company, is a clinical stage biopharmaceutical company specialising in advanced inhaled therapeutics for severe respiratory diseases. The company’s proprietary liposomal drug formulation has been specifically designed for inhaled administration with an exclusively licensed nebulizer technology. Liposomal cyclosporine A for inhalation (L-CsA-i), an investigational drug, is advancing in phase 3 clinical trials as the first […]

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Health & Medicine

PACT: Working with parents and carers to help autism development

Autism is an enduring condition affecting over 1% of people worldwide but with a lack of evidenced therapy to reduce its symptoms. PACT is an early social communication intervention working through parents and carers that is the first to have demonstrated long-term improvements in autism symptoms after therapy within a clinical trial. This relatively low intensity approach is referenced in […]

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Health & Medicine

Using metabolomics and artificial intelligence to explore the universe of the dark metabolome

Professor David Wishart, University of Alberta, is a member of Canada’s national metabolomics laboratory and leads the Human Metabolome Project. His work aims to identify and catalogue metabolites in human tissues, biofluids and the surrounding environment. He has developed a software package called BioTransformer, which is a chemical prediction tool to explore the mysterious dark metabolome. The program combines artificial […]

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Health & Medicine

Overnight orthokeratology: the treatment and control of childhood myopia comes of age

Overnight orthokeratology is a refinement or advancement of the clinical technique of contact lens-based orthokeratology (OK), which has been in use worldwide since the 1960s. It is a corneal refractive therapy used in the treatment of conditions of the eye, principally myopia (short-sightedness), but also presbyopia (long-sightedness), hyperopia (age-related loss of ability to focus on near objects) and astigmatism (an […]

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Health & Medicine

Acoustic waves to brain signals: Identifying the gating spring

The inner workings of our ears have been well understood for some time, but there is still significant debate among researchers over how acoustic vibrations are converted into electrical brain signals. In his research, Dr Jim Hudspeth at The Rockefeller University sheds new light on the discussion, by studying the proteins which connect tiny vibrating hairs in the inner ear with […]

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Health & Medicine

Divine forgiveness may improve mental health

Experiencing divine forgiveness is important to self forgiveness, which, in turn impacts the quality of our relationships as well as our mental health and well-being. Professors Frank D. Fincham and Ross W. May of Florida State University, have presented preliminary evidence that feeling forgiven by God is associated with fewer depressive symptoms in a sample of healthy emerging adults. The authors […]

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Health & Medicine

Preventing nickel allergy using various topcoats for decorative items

Allergic contact dermatitis (ACD) is a form of skin reaction that can be aggravated by nickel causing the skin to become red and itchy. Clive Whittington (Managing Director of C.M. Whittington & Associates Ltd) and Dr W. Y. Lo (Secretary General, Hong Kong Surface Finishing Society) have tested a range of coatings over nickel-based decorative articles such as costume jewellery and watches, to […]

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Health & Medicine

Robotics: the future of liver surgery?

Minimally invasive surgery, sometimes known as keyhole surgery, has proven benefits over traditional open surgery. One type of minimally invasive surgery involves the use of high-tech robotics. Dr Alejandro Mejia of the Methodist Digestive Institute, Dallas, TX, USA, is a leading expert in minimally invasive liver surgery. Along with his team, Dr Mejia uses his first-hand knowledge to investigate different […]

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Health & Medicine

Anagrelide: Finding new use as an adjuvant therapy in cancer management

Dr Richard Franklin, Anagrelide Project Director at SUDA Pharmaceuticals Ltd, is pioneering a radically new application which would see the platelet-lowering drug anagrelide developed as an oromucosal spray formulation. This has the potential to make the most of its recently discovered ability to block cancer cell-stimulated platelet formation and to inhibit cancer cell migration towards platelet precursors (megakaryocytes) while at […]

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Health & Medicine

A valid and reliable clinical outcome measure for patellofemoral instability

Patellofemoral instability can be an extremely debilitating and painful condition. Recognising that the previous outcome measures used to assess patients after treatment were not ideal for patellofemoral instability, Dr Laurie Hiemstra, based at Banff Sport Medicine in Alberta, Canada, designed a new assessment questionnaire specifically for these patients. After testing and researching an initial version, the research team completed further […]

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