Articles
A novel therapy could help patients with active Crohn’s disease
Professor Jørgen Jahnsen and PhD student Kristian Espeland of Akershus University Hospital and University of Oslo are responsible for a new clinical trial which aims to improve symptoms and control the inflammation of Crohn’s disease using Gliolan medication in combination with blue-light photopheresis. This approach will selectively cause the death of pro-inflammatory cells which contribute to the inflammatory bowel disease, […]
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How context influences language processing and comprehension
Words, words, words. They’re all around us, on toothpaste tubes, cell phones, cereal packets and television screens – and that’s before we leave the house! We read thousands of words every day and take our human ability to use language very much for granted. Yet language comprehension is a highly sophisticated process. Aided by technologies which track eye movement and […]
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A new frontier for hate
James Hawdon, Professor of Sociology and Director of the Center for Peace Studies and Violence Prevention at Virginia Tech, USA, has spent many years studying online hate, including hate speech and other forms of cyberviolence. His work has examined how hate speech gets produced, how the hate groups and individuals that produce it become radicalised, how it spreads across the […]
Controlled cortical impact: The animal model that may change brain injury
Traumatic brain injury (TBI) is one of the leading causes of disability and death around the world. To compound this problem, many patients go on to develop anxiety and with little known about the pathophysiology behind this complication, long-lasting and effective treatments are lacking. Using an animal model known as the controlled cortical impact (CCI) model, Dr Ann Marini and […]
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Infectious bronchitis virus affects energy production
Professor Tereza Cristina Cardoso, São Paulo State University, is a qualified veterinarian and her research explores infectious diseases in animals. Her latest work investigates how infectious bronchitis virus affects energy production by macrophage cells. Her research demonstrates that this occurs through disruption of mitochondrial respiration processes, which may have implications for how virus infections in poultry are prevented and treated. […]
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Nanotechnology provides new methods for oral delivery of peptides
One aspect of successful drug development is efficient delivery to affected organs. Most drugs are taken by mouth, travel to the intestines, are absorbed into the bloodstream, and circulated to organs of interest. However, a class of potent drugs known as peptides cannot withstand this abrasive route and are directly injected into veins, under the skin, or into muscles. Injections […]
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Understanding the EGFR mutation
aids the fight against lung cancer
Genetic mutations are known to be responsible for several different types of cancer. One type, known as non-small cell lung cancer, is sometimes caused by mutations in a gene called EGFR. A group of drugs called tyrosine kinase inhibitors are often used to treat patients with this type of cancer. Unfortunately, patients can develop genetic alterations, namely mutation, amplification (an […]
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aids the fight against lung cancer
Volumetric representations
could revolutionise 3D printing
The world of manufacturing is facing a massive game change. For half a century, subtractive manufacturing (SM) has reigned king. In SM, a cutter removes material from a homogeneous block until the desired shape is formed. Additive manufacturing is a major industry waiting just around the corner – and with it, the opportunity to design in a more flexible way. However, […]
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could revolutionise 3D printing
Changing climate: A ‘threat multiplier’ for foodborne and waterborne infectious diseases and antibiotic resistance
Dr Aliyar Cyrus Fouladkhah of Tennessee State University is an Assistant Professor in Public Health Microbiology. His laboratory explores preventive measures for the spread of infectious diseases, antibiotic resistance, and food security in the landscape of changing climate. His research aims to provide better understanding of the ecology, epidemiology and effectiveness of control measures of enteric and environmental pathogens at […]
Unpacking primary biliary cholangitis and its burden in Japan
Itch, fatigue, anxiety, abdominal pain. These are just some of the symptoms faced by primary biliary cholangitis (PBC) patients. The chronic autoimmune disease sees white blood cells attack bile ducts in the liver, causing bile overflow, cell damage and potentially scarring and liver failure. Although it can be successfully managed, some symptoms can linger, hampering patients’ health-related quality of life […]
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