autoimmune disease Archives

Identification of a novel key player in lupus disease opens the door to treatment

Written by

Professor Shiozawa identified a key inducer of lupus disease.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. Through dedicated work, Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying cellular and molecular mechanisms of systemic autoimmunity and identifies a novel key player. Shiozawa demonstrates that overstimulation of the host’s immune system by an immunogenic pathogen kickstarts the generation of […]

How does sleep affect immune-related disease risk?

Written by

Dr Sergio Garbarino researches the links between sleep deprivation, inflammation and the immune system, and chronic diseases such as cancer and neurodegenerative diseases

Sergio Garbarino, adjunct professor in the Department of Neuroscience, Ophthalmology, Genetics, Maternal and Child Health, at the University of Genoa, Italy, is an internationally recognised sleep expert. In his recent work, he explores the interrelationships between sleep deprivation, immunity, inflammation, and chronic diseases. It is well established that sleep is essential for health. However, modern lifestyles are not conducive to […]

The financial toxicity of multiple sclerosis

Written by

Multiple sclerosis (MS) is a neurologic autoimmune disease that is generally diagnosed in young adults. It is a lifelong condition, as it is currently incurable. The medical costs are high, as patients have to cover frequent hospital visits and prescription medications, such as emerging disease modifying drugs. As a result, many patients do not adhere to treatment plans, which further […]

Unpacking primary biliary cholangitis and its burden in Japan

Written by

Primary biliary cholangitis (PBC) can severely impact a patient's health-related quality of life.

Itch, fatigue, anxiety, abdominal pain. These are just some of the symptoms faced by primary biliary cholangitis (PBC) patients. The chronic autoimmune disease sees white blood cells attack bile ducts in the liver, causing bile overflow, cell damage and potentially scarring and liver failure. Although it can be successfully managed, some symptoms can linger, hampering patients’ health-related quality of life […]