Unlocking the mechanism of action of arsenic trioxide in leukaemia

Image of cells under a microscope. One cell is much larger and purple, with a green arrow pointing to it. Researchers have identified the mechanism behind treatment for APL (a type of leukaemia) with ATO - arsenic trioxide - and vitamin A.

The blood cancer acute promyelocytic leukaemia (APL) has recently been transformed from a fatal condition to a curable one, thanks to the development of treatments including vitamin A1 and arsenic trioxide (ATO). Although very effective, the mechanism of action of ATO has remained unclear until now. Changing this is Professor Paul B Tchounwou and his team at Jackson State University, […]

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World Cancer Day 2022: Innovations in cancer research

Despite cancer being a leading cause of death worldwide, detecting cancers early enough to treat them remains a significant challenge. World Cancer Day, held annually on February 4, presents an opportunity to celebrate the advances that have been made, and to reflect on the work still to be done. This blog post brings together five Research Outreach articles that outline […]

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