Cell mechanics – from bench to bedside

Chemical, electrical, and mechanical stimuli trigger activity in a variety of biochemical pathways.

All cells generate and respond to mechanical forces. The role of mechanical forces in cell biology has been understudied, but the forces are essential components of our physiology in health and disease. For example, they are involved in pathologies such as cardiac arrhythmias, muscular dystrophy and metastatic cancer. Dr Frederick Sachs from the University at Buffalo, New York, focuses on […]

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Stem cells could offer hope for muscular dystrophy

Stem cells could offer hope for muscular dystrophy

Muscular dystrophies are genetic conditions that cause muscles to become progressively weaker. Researchers are investigating several novel approaches, including gene and stem cell therapy, to meet the challenges of these serious illnesses. Recently, Dr Yoshitsugu Aoki of the National Center of Neurology and Psychiatry, Tokyo and colleagues have drawn on research from around the world to create a picture of […]

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