Cell mechanics – from bench to bedside

Chemical, electrical, and mechanical stimuli trigger activity in a variety of biochemical pathways.

All cells generate and respond to mechanical forces. The role of mechanical forces in cell biology has been understudied, but the forces are essential components of our physiology in health and disease. For example, they are involved in pathologies such as cardiac arrhythmias, muscular dystrophy and metastatic cancer. Dr Frederick Sachs from the University at Buffalo, New York, focuses on […]

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Patient safety and opioid medications

Patient safety and opioid medications

Hospitalised patients often require appropriate pain relief as part of their treatment. Opioids are effective medications for pain management, but can cause excessive sedation and respiratory depression resulting in patient harm. Dr Carla Jungquist of the University at Buffalo, School of Nursing, and a panel of fellow experts reviewed evidence from the past decade to provide an important update on […]

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