Laboratory lungs: The implications of lung organoids for health and disease

Dr Leibel has developed stem cell-derived lung organoids to learn more about lung development.

Lung disease is a major public health concern. However, research is hindered by the challenges of developing translatable human lung systems in a laboratory setting. Dr Sandra Leibel, neonatologist and Physician Scientist at UCSD and Rady Children’s Hospital in San Diego, USA, is studying lung development and disease mechanisms. In order to do this, she has developed stem cell-derived lung […]

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More than a just a simple powerhouse: Structure and function of mitochondria

More than a just a simple powerhouse Structure and function of mitochondria

Mitochondria are well-known as the “powerhouse” of the cell – but these organelles have many other vital functions. Mitochondria are also heterogeneous, differing in structure and function. Dr Kasturi Mitra of the University of Alabama, Birmingham, Alabama, USA, leads a research team focused on understanding the relationship between structure and function of mitochondria, in both health and disease. Dr Mitra’s […]

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Stem cells could offer hope for muscular dystrophy

Stem cells could offer hope for muscular dystrophy

Muscular dystrophies are genetic conditions that cause muscles to become progressively weaker. Researchers are investigating several novel approaches, including gene and stem cell therapy, to meet the challenges of these serious illnesses. Recently, Dr Yoshitsugu Aoki of the National Center of Neurology and Psychiatry, Tokyo and colleagues have drawn on research from around the world to create a picture of […]

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