Nanoparticles as Trojan horses: A safe and effective way to deliver oncolytic viruses to treat all cancers

Tumour microenvironment, including immune cells and fibroblasts.

Advanced cancer often comes with a lack of treatment options. Immunotherapies like cancer-killing viruses – oncolytic viruses (OVs) – are becoming increasingly popular but are currently limited by their inability to be administered into the blood. However, Dr Faith Howard and Dr Munitta Muthana, researchers at the University of Sheffield in the UK, demonstrate that OVs can be injected into […]

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Nanomedicine for the prevention and treatment of COVID-19 and other viruses

Thomas J Webster develops nanomaterials for novel nanomedicine treatments of viruses such as COVID-19

While many viral infections can be prevented through vaccination, it can take a long time for vaccinations to be developed for new diseases and many people object to themselves or children taking vaccines. There is a high need for quicker, readily available alternative treatments. Serial entrepreneur Professor Thomas J Webster thinks this could be achieved using nanomaterials. Webster’s research has […]

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A mathematical model to predict cancer nanomedicine delivery

graphic of nanoparticles

Dr Zhihui Wang is a researcher at the Houston Methodist Research Institute. He is a leading expert in the fields of computational biology, modelling-aided drug target discovery, biophysical modelling of drug transport, and multiscale cancer modelling. Together with Dr Prashant Dogra, the team have developed a computational model that improves our understanding of the relationship between key nanoparticle properties, the […]

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Metadichol® a novel nano lipid formulation

Metadichol® a novel nano lipid formulation

Many drugs target individual actions of a specific virus or bacteria. However, development and application of a broad-spectrum compound which targets the whole immune response would allow one therapy to have a global application for human disease. Dr P. R. Raghavan, CEO of Nanorx Inc, has invented one such dietary supplement, Metadichol®, which is thought to act via vitamin D […]

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