Curing the incurable: RNA isoforms may hold the key to defeating Alzheimer’s disease

Alzheimer’s disease causes excessive neuronal cell death.

Groundbreaking research on RNA isoforms in Alzheimer’s disease (AD) has revealed another layer of genetic complexity that has been previously overlooked. Using cutting-edge sequencing technology, Dr. Mark Ebbert and colleagues at the Sanders-Brown Center on Aging at the University of Kentucky, USA, performed a detailed analysis of RNA isoforms in the human brain. They discovered multiple, previously unknown RNA isoforms […]

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Decoding fibre secrets of two jute species

jute fibres

Jute is a type of bast fibre plant, of which there are more than hundred species. Jute is used as an affordable natural fibre source for many human purposes. There are only two commercially cultivated species, which have unique fibre characteristics, but they cannot be cross-bred. To gain insight into specific traits of these two species, Basic and Applied Research […]

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How new RNA genes are born

Dr Delihas made an unexpected discovery of an ancestral DNA repeat sequence.

The study of gene birth and evolution focuses on the identification of ancestral genetic sequences, highly conserved during evolution, that can serve as a foundation for gene development. Nicholas Delihas, Professor Emeritus at the Renaissance School of Medicine at Stony Brook University, New York, has identified one such ancestral element and presented data and a model to show how new […]

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From beer to brains: how yeast molecular genetics prove the importance of introns

A research article highlighting the importance of intron retention, using the GCR1 gene found in yeast as a model system.

Scientific discoveries often come from the most unlikely of places, and Dr Tracy Johnson’s work is no exception. Using a yeast system typically used to make beer or bread, Dr Johnson and her team at UCLA have uncovered important genetic findings that could highlight the importance of intron retention during gene expression. Her research looks at the science of gene […]

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