Tag: pancreas
Making strides in veterinary pathology: A dedicated career

Mast cell tumours and pancreatic diseases are common in dogs but also present to a lesser degree in other veterinary species, including cats and horses. For these and many other diseases of veterinary species, diagnostic methods and criteria were not well characterised and made determination of prognosis difficult. Changing this, with decades of research into the pathology of veterinary diseases, […]
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Shedding light on liver metastasis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy, largely as a result of its early spread, or ‘metastasis’, to the liver. Dr Tami Rubinek and Professor Ido Wolf, of the Oncology Division of Tel Aviv Medical Center, Israel, have extensively studied the molecular mechanisms behind liver metastasis in patient tumour samples. They revealed that the absence of certain […]
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Could a serpin antibody help to treat type 1 diabetes?

Research from Dr Jan Czyzyk and his team at the University of Minnesota, USA, explores the balance between proteases and serpins, and how their activity can in turn affect the inflammation and tissue regeneration of pancreatic islet cells. Their findings show that antibodies can be used to change this serpin–protease balance, with interesting impacts. Excitingly, their research opens the possibility […]
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A focus on beta cell mass could help prevent type 2 diabetes

Diabetes is a global health problem expected to affect nearly seven percent of the world’s population by 2035. Treatment broadly focuses on regulating glucose levels, and an increase in the range of pharmacological options means that it is usually possible to manage the condition. However, diabetes cannot be cured. Professor Yoshifumi Saisho from Keio University, Japan, advocates moving the focus […]
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Artificial intelligence allows quick and easy diagnosis of pancreatic cancer

The pancreas is an important organ that regulates food digestion and blood sugar levels. Cancers commonly arise in the pancreas, leading to death for over 50,000 patients per year in the U.S. alone. This is due to a lack of effective therapies and a low survival rate for this disease since symptoms arise only in the late stages of disease. […]
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