Controlling Salmonella in the poultry gut: Diversity is key

Newborn chicks are especially susceptible to Salmonella.

When microorganisms that interact in a specific environment suppress the growth of pathogens, researchers call this ‘pathogen exclusion’. Salmonella is found in poultry intestines and can harm both the birds and humans. To control Salmonella growth, a balance between microorganisms that colonise the poultry gut is necessary. This involves complex interactions between microbes that we don’t yet fully understand. Dr Margie […]

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Exploring the transfer of antibiotic resistance genes within poultry litter

Antibiotic resistance is a major threat to human and animal health.

Antibiotic resistance is a major threat to human and animal health. Bacteria containing antibiotic resistance genes are found in poultry litter, usually from commercial chicken production. Since poultry litter is often used as a soil fertiliser, there is a risk that this antibiotic resistance could be transferred into the soil. Professor John Maurer at Virginia Tech University, USA, has shown […]

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From friend to foe: Food strains share their toxic genes in E. coli

The team investigates plasmid content in food isolates of E. coli and its role as a reservoir for the horizontal transfer of virulence and antibiotic resistance genes to clinical isolates.

Food-borne bacteria can cause life-threatening disease, yet it is still unclear why some strains are tolerated by the host. To find an answer, a project led by Professor Rosa del Carmen Rocha-Gracia (Benemérita Universidad Autónoma de Puebla, Mexico) and Professor Manel Camps (University of California Santa Cruz, USA) analysed the genetic diversity of Escherichia coli populations, comparing isolates from food […]

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Epidemiology–laboratory interactions for developing resilience against future infectious diseases

Salmonella is the leading cause of deaths caused by foodborne illnesses in the USA.

Bacteria are one of the leading causes of public health burden associated with food and waterborne diseases. In addition, they have many abilities that allow them to survive decontamination methods, such as biofilm formation. With the rise in antibiotic resistance and climate change also driving bacterial proliferation, new approaches are needed to mitigate the public health burden of infectious diseases. […]

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One cell’s death is a microbe’s DINNR: How intestinal bacteria use our dying cells as fuel

Dr CJ Anderson and Professor Kodi Ravichandran research the relationship between programmed cell death and bacterial infections in the intestinal tract, with an aim to understand the potential impact that this could have on chemotherapy patients

Until now, a great deal has remained unknown about the relationship between programmed cell death and bacterial infections. However, recent work by Dr CJ Anderson and Professor Kodi Ravichandran from VIB-UGent, Belgium, has shed new light on this topic and introduced a new layer to the complex host–pathogen interaction. The team has shown that dying mammalian cells produce and shed […]

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Bacterial biofilms: A persisting public health challenge

Bacterial biofilms are a notable public health challenge.

Foodborne and waterborne diseases are major global health threats, exacerbated by the ability of bacteria to gain new characteristics, constantly evolve towards increased fitness in their environment, and by developing resilience through biofilm formation. Utilising emerging technologies such as elevated hydrostatic pressure and application of novel bacteriocin and bactericidal compounds, Professor Aliyar Cyrus Fouladkhah and his team in the Public […]

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