Tag: Traumatic brain injury
Understanding neonatal brain injury proteinopathy: Implications for adult-onset neurodegenerative disease
Neonatal encephalopathy is damage to the brain caused by the disruption of its blood supply before and during childbirth and other reasons such as prematurity and maternal-foetal infection. It can often lead to death. Survivors can have long-term cognitive, emotional, and behavioural effects. Lee J Martin, Professor of Anaesthesiology and Critical Care Medicine and Pathology at Johns Hopkins University, USA, […]
Brain Awareness Week 2022
March 14 marks the start of Brain Awareness Week! Spearheaded by the Dana Foundation, the importance of brain research is catapulted onto the global platform between 14th–20th March 2022 – and cerebral successes in the field are celebrated. Research into the brain is vital for saving lives, increasing quality of life and explaining how ‘the little grey cells’ control our […]
A blow to the head impairs the autoregulation of brain blood flow: Neural consequences
Billions of cells make up the human brain. To keep this super-computer functioning, a carefully autoregulated blood supply provides oxygen and nutrients and removes waste products from the brain cells. In addition, cerebral circulation is involved in the regulation of the pressure inside the cranium. But what happens if this autoregulatory process is disrupted? Building on years of research into […]
Controlled cortical impact: The animal model that may change brain injury
Traumatic brain injury (TBI) is one of the leading causes of disability and death around the world. To compound this problem, many patients go on to develop anxiety and with little known about the pathophysiology behind this complication, long-lasting and effective treatments are lacking. Using an animal model known as the controlled cortical impact (CCI) model, Dr Ann Marini and […]
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A potential new treatment for brain injury
Injuries to the brain can have dire consequences, leading to debilitating symptoms and an increased risk of long-term degenerative diseases such as Alzheimer’s disease and amyotrophic lateral sclerosis (ALS). Despite the impact these injuries have on the lives of millions, there are no good treatments or preventative therapies. Associate Professor Daniel Linseman, of the Department of Biological Sciences and the […]
Time for a new approach to severe traumatic brain injury and stroke: Developments in automated, real-time monitoring of brain stem function
Traumatic brain injury and stroke can lead to a potentially fatal condition known as transtentorial herniation (TTH). Monitoring sedated patients for indications that TTH is developing presents many complications. Dr James Stone from New York University has developed a modified version of a test for brain activity in response to sound that shows promise in detecting early indications of TTH. […]