antimicrobial resistance Archives

Combatting antimicrobial resistance using novel small fusion proteins

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Antibiotic resistance is a public health burden worldwide. Alternatives to antibiotics that can counter the detrimental effects of resistant ‘superbugs’ are urgently needed. Dr Xristo Zarate at the Autonomous University of Nuevo Leon in Mexico and his collaborators have worked extensively on developing novel small carrier proteins, like SmbP and CusF3H+, for recombinant protein and peptide expression and purification in […]

Antimicrobial stewardship programmes: Remote consultations can help reduce antibiotic resistance

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The researchers examined the impact of remote consultations with an infectious disease physician.

The increased use of antibiotic therapy to treat infectious diseases is driving up antimicrobial resistance as well as economic and healthcare costs. Antimicrobial stewardship programmes are crucial to monitor and evaluate medication use. Valéria Cassettari, Newton Novato, and Maria Helena Flesch Onuchic at NotreDame Intermédica Advanced Outpatient Clinic in São Paulo, Brazil, explored the impact of remote consultations with an […]

New molecules help battle antimicrobial resistance

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Professor Jonathan Wade and Dr Wenyi Li focus on alternatives to antibiotics including researching peptides and modifying them in a technique called polymerisation to fight the growing issue of antimicrobial resistance.

The overuse of antibiotics over the years has made them less effective in fighting infectious diseases and has led to the emergence of superbugs that are resistant to many different antibiotics. Professor John Wade and Dr Wenyi Li at the University of Melbourne, Australia, together with their collaborators, focus on the development of new antimicrobials to combat infections caused by […]

The silent pandemic: Addressing antimicrobial resistance

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The WHO aims to raise awareness of a silent pandemic, antimicrobial resistance, which is causing difficulties and reducing the effectiveness of certain drugs especially after the COVID-19 pandemic.

Antimicrobial resistance (AMR) is a silent pandemic that poses a huge threat to global health and development. The World Health Organization and its partner organisations are seeking to raise awareness of the issue. One approach is through annual monitoring of progress through the Tripartite AMR Country Self-Assessment Survey (TrACSS), for which the 2021 results are now available, www.amrcountryprogress.org. While significant […]

The CEASE approach: A framework to tackle COVID-19 and other microbial threats

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While the COVID-19 virus continues to spread in many countries worldwide, some researchers are investigating the implications of regularly using antimicrobial products and antibiotics, which could contribute to a concerning phenomenon known as antimicrobial resistance (AMR). Dr Teddie Rahube at Botswana International University of Science and Technology has recently developed CEASE, an approach that addresses some of the challenges associated […]

Proteomics reveals new possibilities in the fight against infection

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The work of Dr Jennifer Geddes-McAlister at the University of Guelph investigates the interactions between hosts and pathogens to uncover new treatment options to combat infections. Her lab uses a range of techniques centered around proteomics, the study of proteins, to progress knowledge of fungal and bacterial infections in humans and agricultural crops. The results of this research can be […]

A Foundation for the future: How the Medical Research Foundation is looking long-term in its medical research funding

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The Medical Research Foundation is funding research that is beneficial to society long-term - one example is the Antimicrobial Research Training Programme.

The Medical Research Foundation (the Medical Research Council’s charitable foundation) believes that investing in long-term research projects – research that will not just be valuable now but also beneficial later – is the key to effective medical advancement. The Foundation steps in to fund the most promising health research that will make the biggest difference, filling gaps left by institutions […]