anti-cancer drugs Archives

Nanoparticles as Trojan horses: A safe and effective way to deliver oncolytic viruses to treat all cancers

Written by

Tumour microenvironment, including immune cells and fibroblasts.

Advanced cancer often comes with a lack of treatment options. Immunotherapies like cancer-killing viruses – oncolytic viruses (OVs) – are becoming increasingly popular but are currently limited by their inability to be administered into the blood. However, Dr Faith Howard and Dr Munitta Muthana, researchers at the University of Sheffield in the UK, demonstrate that OVs can be injected into […]

World Cancer Day 2022: Innovations in cancer research

Written by

Despite cancer being a leading cause of death worldwide, detecting cancers early enough to treat them remains a significant challenge. World Cancer Day, held annually on February 4, presents an opportunity to celebrate the advances that have been made, and to reflect on the work still to be done. This blog post brings together five Research Outreach articles that outline […]

Can anti-cancer drugs be used as an effective therapy for the treatment of Alzheimer’s disease?

Written by

Background Worldwide, around 50 million people have dementia. According to the World Health Organization reports, this number is expected to increase threefold by 2050. Alzheimer’s disease (AD) is the most common type of dementia, which is characterised by deterioration in cognition and behaviour. The underlying aetiopathogenesis of AD is still little understood. The amyloid plaques theory and tau hyperphosphorylation are […]

The role of extra chromosomal circular DNA in rapid adaption to glyphosate resistance in pigweed

Written by

eccDNAs could constitute the targets of the next generation of herbicides and anti-cancer drugs.

Plants, like other living organisms, have genetic stress-avoidance mechanisms that allow them to become resistant to specific chemicals when continuously exposed to them. Dr Christopher Saski from Clemson University and Dr William Molin from the U.S. Department of Agriculture are researching the extrachromosomal circular DNA (eccDNA) structure known as the replicon of pigweed, which contains the EPSPS gene, the gene […]

Targeting melanoma cells with a drug-infused graphene matrix

Written by

The researchers are developing testing platforms for novel therapeutic drug combinations for patients with metastatic melanoma.

Dr Livia Sima of the Institute of Biochemistry of the Romanian Academy and Dr Emanuel Axente of the National Institute for Laser, Plasma, and Radiation Physics in Romania are developing novel platforms for screening of therapeutic drug combinations for patients with metastatic melanoma. Their most recent work involves investigating a method which can be used to screen potential drug candidates. […]