Blog - Page 17 of 165 - Research Outreach

Spiking of urinary biomarker with exercise: A marker of muscle inflammation?

Written by

Seeking a sensitive biomarker of inflammation, Emeritus Professor Isao Okayasu of Kiryu University and Kitasato University, Japan and his colleagues have spent over two decades investigating chronic organ inflammation and […]

How oxidative stress contributes to neurodegenerative diseases

Written by

Hyslop and Chaney use biochemical and computer molecular modelling to probe interaction between H2O2 and GAPDH to identify new molecular targets for treating neurodegeneration and neurodegenerative diseases.

The human brain relies on a constant energy supply that when compromised, neurodegenerative disease ensues, initially disrupting nerve cell communication followed by nerve cell death. Paul Hyslop and Michael Chaney […]

Giants of the deep

Written by

What is it about the submarine world that lends itself to supporting giant versions of the species that exist, much smaller, on land?

Tales of sea monsters have been shared among humans for as long as we have had contact with the sea. Sea serpents, gigantic whales, and massive squids and octopuses have […]

From friend to foe: Food strains share their toxic genes in E. coli

Written by

The team investigates plasmid content in food isolates of E. coli and its role as a reservoir for the horizontal transfer of virulence and antibiotic resistance genes to clinical isolates.

Food-borne bacteria can cause life-threatening disease, yet it is still unclear why some strains are tolerated by the host. To find an answer, a project led by Professor Rosa del […]

Identification of a novel key player in lupus disease opens the door to treatment

Written by

Professor Shiozawa identified a key inducer of lupus disease.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. Through dedicated work, Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying […]

Ending the debate: Routine or selective cholangiography during gallstone surgery?

Written by

Dr Gabriel Sandblom investigates the varying local traditions for intraoperative cholangiography (IOC) during gallstone surgery

Symptomatic gallstones are common in the Western world and treatment of choice is surgical removal of the gallbladder (cholecystectomy). During surgery, an x-ray procedure called intraoperative cholangiography (IOC) gives the […]

Screening frailty: A predictor of healthcare requirements in older people

Written by

Mateo-Abad and Vergara explore a new intervention for people with frailty to improve their functional capacity and delay the occurrence of adverse events related with frailty.

People are living longer, and this is associated with increased pressure on healthcare services. Assessing how much support people need allows resources to be used effectively and patients to receive […]

Metabolic dysfunction: The liver and beyond

Written by

Philipp Kaldis and colleagues have conducted extensive research to elucidate the mechanisms of liver diseases, focusing on metabolism and interorgan crosstalk.

The liver is the centre of our metabolism, with metabolic dysfunction playing a pivotal role in liver diseases and type 2 diabetes. Despite extensive study, the mechanisms underlying these pathologies remain […]

Lead ammunition used by hunters has us all in its sights

Written by

Dr Arnemo has teamed up with scientists worldwide to draw attention to the fact that hunting and lead ammunition remains a significant source of lead exposure in humans and wildlife.

For millions of people, game meat is their primary source of protein, but if the animal is shot using lead (Pb) ammunition, its meat can be toxic. The lead in […]

The Leverhulme Trust: Funding for the future

Written by

Research Outreach speaks to Anna Vignoles, Director of The Leverhulme Trust, about blue skies research and UK university funding.

‘Blue skies’ research is inherently risky as the value and indeed real-world application of research projects cannot be guaranteed. Yet, this type of curiosity-driven research plays an important role, not […]