Prostate cancer Archives

Irreversible electroporation: A safe and effective therapy for low to intermediary prostate cancer risk profiles

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Prostate cancer affects millions of men globally, and is also the third-largest cause of cancer-related deaths among men. Irreversible electroporation (IRE) is one of the more targeted, focal, and minimally aggressive therapies for prostate cancer ablation in comparison to radiotherapy, thermal, or cryo-based ablation methods. Distinguished scientist Professor Olivier Cussenot, surgeon urologist expert for the French National Cancer Institute, is […]

World Cancer Day 2022: Innovations in cancer research

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Despite cancer being a leading cause of death worldwide, detecting cancers early enough to treat them remains a significant challenge. World Cancer Day, held annually on February 4, presents an opportunity to celebrate the advances that have been made, and to reflect on the work still to be done. This blog post brings together five Research Outreach articles that outline […]

Exosome microRNAs as liquid biopsies for the monitoring of prostate cancer

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Neuroendocrine prostate cancer (NEPC) is a highly aggressive variant of prostate cancer that emerges in response to hormone therapy. Dr Sharanjot Saini and her staff, from the Medical College of Georgia at Augusta University, USA, are studying exosomes – nano-sized vesicles that transfer lipids, proteins, or genetic information between cells. These could be used as a source of biomarkers to […]

The role of testosterone in SARS-CoV-2 infection

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Dr Marta Camici investigates the link between low testosterone levels and the severity of COVID-19 cases in patients

Data from multiple countries has shown gender imbalances in COVID-19 severity and risk of mortality, with worse outcomes seen in men. To explore why male gender is a major risk factor for more severe disease, Marta Camici, of The Lazzaro Spallanzani National Institute for Infectious Diseases (IRCCS), has explored the links between testosterone and COVID-19. Her research findings suggest that […]

New hope for accurate prognosis of prostate and blood cancers using 3D telomeric imaging and Lamin A/C

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Genetic mutations are known to be a factor in the development of cancer.

Professor Sabine Mai of the University of Manitoba, Canada, has been examining the links between genomic instability and cancer using 3D imaging of the genome. She has also collaborated on cutting-edge research, utilising a potential biomarker called Lamin A/C for determining the aggressiveness of Hodgkin’s lymphoma and the severity of Multiple Myeloma. This research is a first step toward circumventing […]

AMP-activated kinase as a therapeutic target in prostate cancer

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Prostate cancer is one of the leading causes of mortality among men worldwide.

Pharmacological treatment of prostate cancer has advanced significantly in recent years. However, while the newest therapies are initially effective in reducing tumour size, most patients eventually develop drug resistance and the recurrence of malignant spread. Professor Inés Díaz-Laviada and her team at the Alcala University in Madrid, Spain, have demonstrated that long-term treatments may induce the transformation of cancer cells […]

NPCR: Next generation cancer register

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Knowledge is power and in this modern age, data is often our most valuable commodity. Nowhere is this truer than in healthcare, where patient data is revolutionizing the way we treat diseases such as cancer. To that end, the National Prostate Cancer Register (NPCR) is providing a valuable resource for physicians, patients, and researchers. And it has already contributed to […]