Tag: USA
A parametric framework for multidimensional linear regression
While Ordinary Least Squares regression establishes fundamental concepts in data analysis, it requires the independent variable to be error-free and the error term to be constant. Dr Stanley Luck, statistics consultant and founding member of Vector Analytics LLC in the US, has developed an innovative parametric framework for multidimensional linear regression. This provides a more general framework for establishing measurement […]
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Why aren’t more human resource leaders champions of diversity?
Significant global groundswells of social activism over the last few years have highlighted the issue of diversity. There is now increasing pressure on organisations to address diversity, especially among leadership. Within such organisations, managing this process usually falls within the ambit of the human resource leader, so their sensitivity to issues of culture and diversity is key. Dr Lauren Turner […]
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Exosome microRNAs as liquid biopsies for the monitoring of prostate cancer
Neuroendocrine prostate cancer (NEPC) is a highly aggressive variant of prostate cancer that emerges in response to hormone therapy. Dr Sharanjot Saini and her staff, from the Medical College of Georgia at Augusta University, USA, are studying exosomes – nano-sized vesicles that transfer lipids, proteins, or genetic information between cells. These could be used as a source of biomarkers to […]
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Male infertility and the genesis of mature sperm cells
About 10% of all males in the United States who are attempting to conceive suffer from infertility. Dr Rajakumar Anbazhagan, Dr Maria L. Dufau and Dr Kavarthapu Raghuveer from the National Institutes of Health, USA, aim to understand the biochemical pathways behind male factor infertility to devise a better strategy to address the issue effectively. The researchers identified a protein […]
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A solution to dark matter: New evidence for hydrogen’s second flavour
Following on from his previous research, Professor Eugene Oks at Auburn University, Alabama, presents even further evidence that an explanation for dark matter could lie with a ‘second flavour’ of hydrogen atoms. This time, he analyses the results of an extensive survey of millions of galaxies to assess the characteristics of ‘gravitational lensing’: a light-bending effect, first predicted by Einstein. […]
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Stem cell-based cartilage regeneration technology
Harnessing the regeneration ability of stem cells, researchers are making strides in the treatment of large cartilage defects of the knee. A collaborative team including Dr Khay-Yong Saw, Dr Reza Ng, Dr Caroline Jee (Kuala Lumpur Sports Medicine Centre, Malaysia), and Dr Adam Anz (Andrews Research and Education Foundation, Florida, USA) demonstrate the safety and efficacy of peripheral blood stem […]
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The M-Factor: An experiential learning student competition
How might the format of reality TV shows be adapted to the academic environment to help engineering students develop management skills? That was the aim of a research project devised by Professor Theomary Karamanis, from Cornell University in New York in the United States, and Professor Allan MacKenzie, from McMaster University in Ontario, Canada. The findings show that not only […]
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Geopolitics of the illicit global economy
‘Black spots’ are the safe havens that offer a base of operations for transnational criminal, insurgent, and terrorist organisations. At the Maxwell School of Citizenship and Public Affairs of Syracuse University, USA, Professors Stuart Brown and Margaret Hermann are attempting to shed greater light on these geopolitical places by looking at the intra-regional, cross-national, and international linkages among them. Their […]
Drug-adapted RET mutations
RET is a protein tyrosine kinase that is upregulated and activated in many diverse forms of cancer. Treatments using RET-specific inhibitors have been highly effective, but the threat of resistance to these drugs looms. For this reason, Dr Jie Wu and Dr Blaine Mooers from the University of Oklahoma, together with Dr Vivek Subbiah from the University of Texas, decided […]
Could a serpin antibody help to treat type 1 diabetes?
Research from Dr Jan Czyzyk and his team at the University of Minnesota, USA, explores the balance between proteases and serpins, and how their activity can in turn affect the inflammation and tissue regeneration of pancreatic islet cells. Their findings show that antibodies can be used to change this serpin–protease balance, with interesting impacts. Excitingly, their research opens the possibility […]
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