cancer Archives

Most popular articles published in 2021

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Close up of the Earth at night as viewed from space.

It’s been a busy year here at Research Outreach. We’ve been lucky enough to collaborate with researchers working on projects that span some of 2021’s most talked-about topics, including the impact of social media on public discourse, the effectiveness of face masks, and innovations in financial technology. Read on to explore our top ten most popular articles of 2021 – […]

Drug-adapted RET mutations

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The active RET protein has been seen in many types of thyroid cancers.

RET is a protein tyrosine kinase that is upregulated and activated in many diverse forms of cancer. Treatments using RET-specific inhibitors have been highly effective, but the threat of resistance to these drugs looms. For this reason, Dr Jie Wu and Dr Blaine Mooers from the University of Oklahoma, together with Dr Vivek Subbiah from the University of Texas, decided […]

A new concept for the treatment of brain cancer

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Glioblastoma Multiforme (GBM) is a serious form of brain cancer with highly limited treatment options. Through extensive clinical trials, dendritic cell vaccines have been shown to prolong life in patients. However, a successful randomised controlled clinical trial (RCT) has not been carried out. Professor Stefaan Van Gool, Medical Director of the Immuno-Oncological Center (IOZK) in Cologne, aims to understand why. […]

New hope for accurate prognosis of prostate and blood cancers using 3D telomeric imaging and Lamin A/C

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Genetic mutations are known to be a factor in the development of cancer.

Professor Sabine Mai of the University of Manitoba, Canada, has been examining the links between genomic instability and cancer using 3D imaging of the genome. She has also collaborated on cutting-edge research, utilising a potential biomarker called Lamin A/C for determining the aggressiveness of Hodgkin’s lymphoma and the severity of Multiple Myeloma. This research is a first step toward circumventing […]

Maryland Stem Cell Research Fund: Cutting-edge regenerative medicine

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The Maryland Stem Cell Research Fund (MCSRF) is devoted to developing and supporting innovative research into all aspects of stem-cell-based technologies. Through its diverse program structure, the MSCRF is intimately involved in every stage of the stem cell journey – from pre-clinical lab discovery to clinical patient trials. Importantly, it remains forward thinking, ensuring the next generation of researchers have […]

Asbestos and bile duct cancer

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Professor Giovanni Brandi and Dr Simona Tavolari, from the University of Bologna, study the association between asbestos exposure and intrahepatic cholangiocarcinoma (ICC). Case-control analyses in Italy and four Nordic countries found strong associations between occupational exposure to asbestos and ICC. Therefore, asbestos is suggested as a risk factor for ICC development. This could be due to asbestos fibres becoming trapped […]

Is it possible to train medical experts using Artificial Intelligence (AI) training methods?

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Artificial Intelligence (AI) is rapidly gaining traction in all walks of human life. Today, apps that recognise and respond to human speech and self-driving cars are no longer the stuff of science fiction but facts of life. But what if AI – more specifically, a method called deep learning that is used for training smart computers – were used to […]

Novel cancer therapeutics could target ion channels

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Although gynaecological cancers are amongst the most lethal cancers in women, treatments for the advanced stages of these cancers are scarce. Dr Saverio Gentile at the University of Illinois Cancer Center has been researching potassium ion channels as a potential target for novel cancer therapeutics. He has found that the use of potassium channel activators greatly reduced cell motility, tumour […]

The role of extra chromosomal circular DNA in rapid adaption to glyphosate resistance in pigweed

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eccDNAs could constitute the targets of the next generation of herbicides and anti-cancer drugs.

Plants, like other living organisms, have genetic stress-avoidance mechanisms that allow them to become resistant to specific chemicals when continuously exposed to them. Dr Christopher Saski from Clemson University and Dr William Molin from the U.S. Department of Agriculture are researching the extrachromosomal circular DNA (eccDNA) structure known as the replicon of pigweed, which contains the EPSPS gene, the gene […]

Quality of life for family caregivers is impacted by satisfaction with care

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Cancer does not only affect the patient but their caregiver.

Cancer has an emotional and physical impact on caregivers as well as patients. If relatives are not happy with the care they are able to provide for the patient, this can impair their quality of life. Dr Miki Morishita-Kawahara at the Tokyo Women’s Medical University aims to understand better the factors that influence the quality of life of family caregivers […]